Lipoid proteinosis (LP) is a rare, inherited condition that progresses gradually with multisystemic manifestations. Histopathologic characteristics can be understated, delaying the diagnosis if a high degree of suspicion is not present.
Larkin, S and Blixit, Elizabeth K., "Lipoid Proteinosis: Unfamiliar Skin Findings Delay Diagnosis" (2018). Articles. 77.